Effect of microtubule-targeting drugs on cell–cell and cell–matrix junctions in tumor epithelial cells

Tonutti et al
Anti-Cancer Drugs 22 (3) March 2011
ISSN: 0959-4973 • Frequency: 10/year • Subscribe Now

This study investigated the effects of microtubuletargeting drugs, which either destabilize (the Vinca alkaloid vincristine) or stabilize (the taxane derivative docetaxel) microtubules, on the cell–cell and cell–matrix adhesive junctions of Caco-2 tumor epithelial cells, using fluorescence imaging and functional assays.

 Read Introduction /Read this Article

Don't miss out - further Free LWW Content is available for registered users! Log into your account or register here to read these articles