Gamma-glutamyl transpeptidase and a-fetoprotein: are they predictors of treatment response in patients with chronic hepatitis C?
Hepatitis C virus is a leading cause of chronic liver disease. Elevated serum a-fetoprotein (AFP) has been used as a marker for hepatic regeneration after the destruction of hepatocyte in viral hepatitis. Recently, c-glutamyl transpeptidase (GGT) has also been taken into account in the evaluation of patients with chronic hepatitis C (CHC). This study aimed to examine the association between serum AFP and serum GGT levels, and treatment outcome in patients with CHC treated with pegylated interferon and ribavirin.
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