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You are here: Home » Anaesthesiology » Sex and pregnancy on the potency of intrathecal bupivacaine

Effect of sex and pregnancy on the potency of intrathecal bupivacaine: determination of ED50 for motor block with the up–down sequential allocation method

Cover of European Journal of AnaesthesiologyCamorcia et al
European Journal of Anesthesiology 28 (4) April 2011
ISSN: 0265-0215 • Frequency: 12/year • Subscribe Now

This study aims to investigate whether sex or pregnancy may change the potency of bupivacaine, using the up–down sequential allocation model to estimate the intrathecal median effective dose (ED50) for motor block in male, female and pregnant patients.


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